EFSA Finds No Safe Level for Berberine at Any Dose: EU Prohibition Is Now the Likely Outcome

EFSA’s preliminary review has found no safe intake level for berberine at any dose, with a final opinion due early 2027 likely to trigger an EU-wide prohibition. Brands selling berberine supplements in Europe should plan reformulation ahead of that opinion.
EU Vitamin and Mineral Dose Limits: Public Consultation Opens Q3 2026

The EU Commission opens a public consultation on harmonised vitamin and mineral maximum permitted levels in Q3 2026, with a draft regulation due Q1 2028. High-dose B vitamins, vitamin D and sports nutrition products face the most reformulation risk.
EFSA’s Positive Safety Opinion on NMN Opens the EU Authorization Path

EFSA published a positive safety opinion on beta-NMN on May 13, 2026, confirming 300mg per day safe for the general adult population and formally opening the EU Novel Food authorization pathway. For US sports nutrition brands, this is the signal that EU market access for NMN is now a near-term target, not a regulatory unknown. EU authorization typically follows a positive EFSA opinion within five to seven months, putting the practical entry window at Q4 2026 to Q1 2027.